Talk to us at the Pharmacovigilance Strategy Meeting USA - Boston May 16 2022 

biologit are sponsors at the Pharmacovigilance Strategy Meeting USA 2022 (May 16 in Boston). Looking forward to seeing you there!

VIP code - BIOL2022VIP

Validation and Transparency in AI systems for Pharmacovigilance: a case study applied to the medical literature monitoring of adverse events

Recent advances in artificial intelligence applied to biomedical text are opening exciting opportunities for improving pharmacovigilance activities currently burdened by the ever growing volumes of real world data. To fully realize these opportunities, existing regulatory guidance and industry best practices should be taken into consideration in order to increase the overall trustworthiness of the system and enable broader adoption. In this paper we present a case study on how to operationalize existing guidance for validated AI systems in pharmacovigilance focusing on the specific task of medical literature monitoring (MLM) of adverse events from the scientific literature. We describe an AI system designed with the goal of reducing effort in MLM activities built in close collaboration with subject matter experts and considering guidance for validated systems in pharmacovigilance and AI transparency. In particular we make use of public disclosures as a useful risk control measure to mitigate system misuse and earn user trust. In addition we present experimental results showing the system can significantly remove screening effort while maintaining high levels of recall (filtering 55% of irrelevant articles on average, for a target recall of 0.99 on suspected adverse articles) and provide a robust method for tuning the desired recall to suit a particular risk profile.

Talk to us at the World Drug Safety Congress Europe - Amsterdam Oct 6/7 2021 

biologit are sponsors at the 2021 World Drug Safety Congress Europe (October 6/7 in Amsterdam) and will present a talk on AI for medical literature screening. Looking forward to seeing you there!

Meet the woman using AI to improve clinical safety - biologit featured in Silicon Republic (Jul-2021)

biologit was featured in Silicon Republic's Automation Week with an article with co-founder Nicole Baker and how automation will become increasingly important for screening scientific literature.

biologit featured in Enterprise Ireland's Big Ideas 2020 innovation showcase (Nov-2020)

Big Ideas 2020 is Enterprise Ireland's annual showcase of investor-ready startups, taking place online on 25 November. Biologit is one of the featured startups presenting pitches to Ireland's investment community.

Watch: Co-founder Nicole Baker taking part on woman in STEM webinar (Nov-2020).

Four women blazing a trail in STEM will share the story of their journey to where they are now and plans for the future. Our co-founder, Nicole Baker is taking part.

Pragmatic machine learning to reduce medical literature screening workloads - DIA Regulatory Science Forum (Oct-2020)

The biologit team in collaboration with Trinity College Dublin presented experimental results on the use of AI for reducing medical literature screening workloads while maintaining high quality of results.

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See also our recent blog post discussing the results.

Listen: Medical literature monitoring and pharmacovigilance - ADAPT Radio podcast.

In this podcast, co-founder Nicole baker discusses pharmacovigilance, literature monitoring and how AI can address the industry challenges.